Bodies of evidence? Lymphoglandular bodies in aspirate smears of bone marrow involved by aggressive large B-cell lymphoma.

A 79-year-old woman presented with hypercalcemia and a mediastinal mass identified by computed tomography scan. Further imaging revealed several intracranial lesions that were not intraparenchymal, as well as a large periaortic mass with diffuse abdominal lymphadenopathy. A biopsy of the mediastinal mass yielded a diagnosis of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. A staging bone marrow examination was performed and revealed extensive involvement by an aggressive appearing large B-cell lymphoma. A striking number of lymphoglandular bodies were present in the bone marrow aspirate smears.